| RARG |
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| Наявні структури |
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| PDB | Пошук ортологів: H3BMH6 PDBe H3BMH6 RCSB |
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| Список кодів PDB | | 1EXA, 1EXX, 1FCX, 1FCY, 1FCZ, 1FD0, 2LBD, 3LBD, 4LBD | | |
| Ідентифікатори |
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| Символи | RARG, NR1B3, RARC, retinoic acid receptor gamma, RARgamma |
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| Зовнішні ІД | OMIM: 180190 MGI: 97858 HomoloGene: 20263 GeneCards: RARG |
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| Реагує на сполуку |
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| adapalene, alitretinoin, palovarotene, tamibarotene, tazarotene, третиноїн[1] |
| Онтологія гена |
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| Молекулярна функція | • sequence-specific DNA binding
• RNA polymerase II transcription regulatory region sequence-specific DNA binding
• zinc ion binding
• зв'язування з іоном металу
• steroid hormone receptor activity
• GO:0001948, GO:0016582 protein binding
• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
• DNA binding
• retinoid X receptor binding
• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
• GO:0000975 transcription cis-regulatory region binding
• transcription factor binding
• nuclear receptor coactivator activity
• signaling receptor activity
• GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity
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| Клітинна компонента | • integral component of membrane
• нуклеоплазма
• клітинне ядро
• transcription regulator complex
• RNA polymerase II transcription regulator complex
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| Біологічний процес | • regulation of cell size
• growth plate cartilage development
• cellular response to retinoic acid
• gland development
• GO:0009373 regulation of transcription, DNA-templated
• negative regulation of cartilage development
• response to retinoic acid
• multicellular organism growth
• negative regulation of cell differentiation
• bone morphogenesis
• chondrocyte development
• negative regulation of apoptotic process
• retinal pigment epithelium development
• transcription, DNA-templated
• epithelium development
• embryonic camera-type eye development
• reproductive structure development
• limb development
• face development
• neural tube closure
• negative regulation of chondrocyte differentiation
• Harderian gland development
• prostate gland epithelium morphogenesis
• regulation of myelination
• GO:1901313 positive regulation of gene expression
• retina development in camera-type eye
• positive regulation of cell population proliferation
• growth plate cartilage chondrocyte growth
• canonical Wnt signaling pathway
• регуляція експресії генів
• camera-type eye development
• transcription initiation from RNA polymerase II promoter
• regulation of myeloid cell differentiation
• bone development
• trachea cartilage development
• anterior/posterior pattern specification
• glandular epithelial cell development
• steroid hormone mediated signaling pathway
• GO:1901227 negative regulation of transcription by RNA polymerase II
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• embryonic hindlimb morphogenesis
• retinoic acid receptor signaling pathway
• negative regulation of cell population proliferation
• embryonic eye morphogenesis
• positive regulation of apoptotic process
• positive regulation of programmed cell death
• cellular response to leukemia inhibitory factor
• multicellular organism development
• hormone-mediated signaling pathway
• диференціація клітин
• response to lipid
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| Джерела:Amigo / QuickGO | |
| Ортологи |
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| Види | Людина | Миша |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (мРНК) | | NM_000966
NM_001042728
NM_001243730
NM_001243731
NM_001243732 |
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| RefSeq (білок) | | NP_000957
NP_001036193
NP_001230659
NP_001230660
NP_001230661 |
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| Локус (UCSC) | Хр. 12: 53.21 – 53.23 Mb | Хр. 15: 102.14 – 102.17 Mb |
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| PubMed search | [2] | [3] |
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| Вікідані |
| Див./Ред. для людей | Див./Ред. для мишей |
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