Alclofenac
Chemical compound
- M01AB06 (WHO)
- 2-(3-chloro-4-prop-2-enoxyphenyl)acetic acid
- 22131-79-9
- 30951
- 28714 Y
- M9CP5H21N8
- D01252 Y
- ChEMBL94081 Y
- DTXSID4020038
- Interactive image
- Clc1cc(ccc1OC\C=C)CC(=O)O
InChI
- InChI=1S/C11H11ClO3/c1-2-5-15-10-4-3-8(6-9(10)12)7-11(13)14/h2-4,6H,1,5,7H2,(H,13,14) Y
- Key:ARHWPKZXBHOEEE-UHFFFAOYSA-N Y
Alclofenac is a nonsteroidal anti-inflammatory drug (NSAID).
Synthesis
References
- ^ Gaviraghi G, Banfi S, Cornelli U, Pinza M, Pifferi G (April 1977). "Synthesis and antiinflammatory activity of 3-chloro-4-cyclopropylmethoxyphenylacetic acid and its alpha-methyl homologue". Il Farmaco; Edizione Scientifica. 32 (4): 286–95. PMID 862882.
- ^ CA 831040, Gillet C, Buu HN, Lambelin G, "Substituted Phenylacetic Acids and Processes of Preparation Thereof", published 30 December 1969, assigned to Madan Ag
- ^ US 3824277, Gillet C, Buu HN, Lambelin G, "4-Allyloxy-3-chloro-phenyl-acetic acid", published 16 July 1974, assigned to Madan Ag
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pyrazolidines
and related substances
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- COX-inhibiting nitric oxide donator: Naproxcinod
acids (fenamates)
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combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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