Bendazac
Chemical compound
- M02AA11 (WHO) S01BC07 (WHO)
- [(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
- 20187-55-7 Y
- 2313
- 2223 Y
- G4AG71204O
- D01594 Y
- CHEBI:31257 N
- ChEMBL1089221 Y
- DTXSID1048334
- Interactive image
- O=C(O)COc2nn(c1ccccc12)Cc3ccccc3
InChI
- InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) Y
- Key:BYFMCKSPFYVMOU-UHFFFAOYSA-N Y
Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.[1]
Synthesis
Principal action is inhibition of protein denaturation.
Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).
See also
- Benzydamine
References
- ^ Balfour JA, Clissold SP (April 1990). "Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts". Drugs. 39 (4): 575–96. doi:10.2165/00003495-199039040-00007. PMID 2190795. S2CID 46956362.
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pyrazolidines
and related substances
- Aceclofenac
- Acemetacin
- Alclofenac
- Amfenac
- Bendazac
- Bromfenac
- Bufexamac
- Bumadizone
- Diclofenac
- Difenpiramide
- Etodolac
- Felbinac
- Fenclozic acid
- Fentiazac
- Indometacin
- Indometacin farnesil
- Isoxepac
- Ketorolac
- Lonazolac
- Mofezolac
- Oxametacin
- Prodolic acid
- Proglumetacin
- Sulindac
- Tiopinac
- Tolmetin
- Zomepirac†
- Ampiroxicam
- Droxicam
- Isoxicam
- Lornoxicam
- Meloxicam
- Piroxicam
- Pivoxicam
- Tenoxicam
derivatives (profens)
- Alminoprofen
- Benoxaprofen†
- Carprofen‡
- Dexibuprofen
- Dexketoprofen
- Fenbufen
- Fenoprofen
- Flunoxaprofen
- Flurbiprofen
- Ibuprofen#
- Ibuproxam
- Indoprofen†
- Ketoprofen
- Loxoprofen
- Miroprofen
- Naproxen
- Oxaprozin
- Pelubiprofen
- Piketoprofen
- Pirprofen
- Suprofen
- Tarenflurbil
- Tepoxalin‡
- Tiaprofenic acid
- Vedaprofen‡
- Zaltoprofen
- COX-inhibiting nitric oxide donator: Naproxcinod
acids (fenamates)
(coxibs)
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
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