Afurolol
Chemical compound
- none
- 7-[3-(tert-Butylamino)-2-hydroxy-propoxy]-3H-isobenzofuran-1-one
- 65776-67-2 N
- 176877
- 154050 Y
- WQ1WRV49R9
- ChEMBL1742435 N
- DTXSID70867182
- Interactive image
- O=C1OCc2cccc(OCC(O)CNC(C)(C)C)c12
InChI
- InChI=1S/C15H21NO4/c1-15(2,3)16-7-11(17)9-19-12-6-4-5-10-8-20-14(18)13(10)12/h4-6,11,16-17H,7-9H2,1-3H3 Y
- Key:NFXPPCYKSAAUMQ-UHFFFAOYSA-N Y
Alfurolol is a beta blocker.[1][2]
References
- ^ "The Use of Common Stems in the Selection of International Nonproprietary Names (INN) for Pharmaceutical Substances: Alphabetical list of stems together with corresponding INNs". Archived from the original on March 7, 2012.
- ^ Narimatsu S, Takemi C, Kuramoto S, Tsuzuki D, Hichiya H, Tamagake K, Yamamoto S (May 2003). "Stereoselectivity in the oxidation of bufuralol, a chiral substrate, by human cytochrome P450s". Chirality. 15 (4): 333–9. doi:10.1002/chir.10212. PMID 12666241.
- v
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(antagonize α-adrenergic
vasoconstriction)
Central |
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Peripheral |
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Serotonin receptor antagonists | |
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Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension) |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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