Talinolol
Names | |
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IUPAC name (RS)-1-[4-[3-(tert-Butylamino)-2-hydroxypropoxy]phenyl]-3-cyclohexylurea | |
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ECHA InfoCard | 100.228.618 |
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InChI
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Properties | |
Chemical formula | C20H33N3O3 |
Molar mass | 363.502 g·mol−1 |
Pharmacology | |
C07AB13 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Talinolol is a beta blocker.[1]
Stereochemistry
Talinolol contains a stereocenter and consists of two enantiomers. This is a racemate, i.e. a 1: 1 mixture of (R)- and the (S)-forms:[2]
Enantiomers of talinolol | |
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(R)-talinolol CAS number: 71369-60-3 | (S)-talinolol CAS number: 71369-59-0 |
References
- ^ Abmann, I. (1995). "The actions of talinolol, a β1-selective beta blocker, in cardiac arrhythmia and acute myocardial infarction". Current Medical Research and Opinion. 13 (6): 325–342. doi:10.1185/03007999509110493. PMID 8829891.
- ^ F. v. Bruchhausen, G. Dannhardt, S. Ebel, A. W. Frahm, E. Hackenthal, U. Holzgrabe (Hrsg.): Hagers Handbuch der Pharmazeutischen Praxis: Band 9: Stoffe P-Z, Springer Verlag, Berlin, Aufl. 5, 2014, S. 767, ISBN 978-3-642-63389-8.
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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