Pynazolam
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Formula | C16H12N6O2 |
Molar mass | 320.312 g·mol−1 |
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Pynazolam is a triazolobenzodiazepine derivative first invented in the 1970s,[1] which has in more recent years been sold online as a designer drug. Anecdotal reports and in silico studies suggest it has relatively potent hypnotic and sedative effects.[medical citation needed] Pynazolam is a powerful serotonin releaser similar to nimetazepam[2] which increases hypnotic activity and euphoria. Anecdotal evidence has also suggested that it's subjective effects are similar to methaqualone[3] although unlike methaqualone, it cannot be smoked due to high melting-point.
Limited pharmacological data is available[4] although their is an increasing availability of the compound for research purposes.[5]
See also
- Clonazolam
- Flunitrazolam
- Nitrazolam
- Pyeazolam
- Pyrazolam
- List of benzodiazepines
References
- ^ US 3970664, Sternbach LH, Walser A, "Preparation of triazolo benzodiazepines.", issued 20 July 1976, assigned to Hoffmann-LaRoche, Inc.
- ^ Pranzatelli, Michael R. (1989). "Benzodiazepine-induced shaking behavior in the rat: Structure-activity and relation to serotonin and benzodiazepine receptors". Experimental Neurology. 104 (3): 241–250. doi:10.1016/0014-4886(89)90036-8.
- ^ https://bluelight.org/xf/threads/flubromazolam-retrospective-6-years-with-the-knockout-night-nurse.892802/page-7
- ^ Catalani V, Floresta G, Botha M, Corkery JM, Guirguis A, Vento A, et al. (January 2023). "In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines". Chemical Biology & Drug Design. 101 (1): 40–51. doi:10.1111/cbdd.14119. hdl:2299/25749. PMID 35838189.
- ^ https://pubchem.ncbi.nlm.nih.gov/compound/20368157
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