Piperocaine
Chemical compound
- none
- 3-(2-Methylpiperidin-1-yl)propyl benzoate
- 136-82-3
Y
- 10782
- 10326
N
- F66XUI6GZL
- ChEMBL127865 N
- DTXSID8048315
- Interactive image
- CC1CCCCN1CCCOC(C2=CC=CC=C2)=O
InChI
- InChI=1S/C16H23NO2/c1-14-8-5-6-11-17(14)12-7-13-19-16(18)15-9-3-2-4-10-15/h2-4,9-10,14H,5-8,11-13H2,1H3N
- Key:YQKAVWCGQQXBGW-UHFFFAOYSA-NN
N
Y (what is this?) (verify)Piperocaine is a local anesthetic drug developed in the 1920s and used as its hydrochloride salt for infiltration and nerve blocks.
Synthesis
Alkylation between 3-chloropropyl benzoate [942-95-0] (1) and Pipicoline [109-05-7] (2) provides piperocaine (3).
See also
- Hexylcaine
References
Further reading
- Tiedt TN, Albuquerque EX, Bakry NM, Eldefrawi ME, Eldefrawi AT (November 1979). "Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor". Molecular Pharmacology. 16 (3): 909–21. PMID 316855.[1]</ref>
- v
- t
- e
Local anesthetics (primarily sodium channel blockers) (N01B)
| Aminobenzoic | |
|---|---|
| Benzoic |
|
| ArCO2- (not para-amino or Ph) |
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
 | This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
- v
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- ^ Costich, Emmett R. (1950-02-01). "A Preliminary Study of the Efficiency of Piperocaine Hydrochloride as a Local Anesthetic in Dental Surgery". The Journal of the American Dental Association. 40 (2): 163–169. doi:10.14219/jada.archive.1950.0022. ISSN 0002-8177. PMID 15402120.
