Glukozamin-fosfat N-acetiltransferaza
| Glukozamin-fosfat N-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Glukozamin-fosfat N-acetiltransferaza homodimer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.3.1.4 | ||||||||
| CAS broj | 9031-91-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glukozamin-fosfat N-acetiltransferaza (EC 2.3.1.4, fosfoglukozaminska transacetilaza, fosfoglukozaminska acetilaza, glukozamin-6-fosfatna acetilaza, D-glukozamin-6-P N-acetiltransferaza, aminodezoksiglukozafosfatna acetiltransferaza, glukozamin 6-fosfatna acetilaza, glukozamin 6-fosfatna N-acetiltransferaza, N-acetilglukozamin-6-fosfatna sintaza, fosfoglukozaminska N-acetilaza, glukozamin-6-fosfatna N-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:D-glukozamin-6-fosfat N-acetiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + D-glukozamin 6-fosfat KoA + N-acetil-D-glukozamin 6-fosfat
Reference
- ↑ Davidson, E.A. (1966). „Glucosamine 6-phosphate N-acetylase”. Methods Enzymol. 9: 704-707.
- ↑ Davidson, E.A., Blumenthal, H.J. and Roseman, F. (1957). „Glucosamine metabolism. II. Studies of glucosamine 6-phosphate N-acetylase”. J. Biol. Chem. 226: 125-133. PMID 13428743.
- ↑ Pattabiraman, T.N. and Bachhawat, B.K. (1962). „Purification of glucosamine-6-phosphate N-acetylase from sheep brain”. Biochim. Biophys. Acta 59: 681-689. PMID 14484387.
- ↑ Boehmelt, G., Fialka, I., Brothers, G., McGinley, M.D., Patterson, S.D., Mo, R., Hui, C.C., Chung, S., Huber, L.A., Mak, T.W. and Iscove, N.N. (2000). „Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association”. J. Biol. Chem. 275: 12821-12832. PMID 10777580.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Glucosamine-phosphate+N-acetyltransferase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
Glukozamin-fosfat_N-acetiltransferaza