Tigloidine
Chemical compound
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Trade names | Tropigline |
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ECHA InfoCard | 100.007.101 |
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Formula | C13H21NO2 |
Molar mass | 223.316 g·mol−1 |
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Tigloidine is a tropane alkaloid that naturally occurs as a minor constituent of a number of solanaceous plants, including Duboisia myoporoides,[1] Physalis peruviana,[2] and Mandragora turcomanica.
It was formerly marketed as an antiparkinsonian drug[3] under the trade name Tropigline.[4]
References
- ^ Barger G, Martin WF, Mitchell W (1937). "383. The minor alkaloids of Duboisia myoporoides". Journal of the Chemical Society (Resumed): 1820. doi:10.1039/JR9370001820. hdl:1842/35366.
- ^ Beresford PJ, Woolley JG (1974). "Biosynthesis of ticloidine in Physalis peruviana". Phytochemistry. 13 (10): 2143–2144. Bibcode:1974PChem..13.2143B. doi:10.1016/0031-9422(74)85016-8.
- ^ "Approved Names". British Medical Journal. 1 (5080): 1175. 1958. doi:10.1136/bmj.1.5080.1175. PMC 2028565.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 1663–. ISBN 978-3-88763-075-1.
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III