Protein-coding gene in the species Homo sapiens
SLC38A5 |
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Identifiers |
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Aliases | SLC38A5, JM24, SN2, SNAT5, pp7194, solute carrier family 38 member 5 |
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External IDs | OMIM: 300649; MGI: 2148066; HomoloGene: 24917; GeneCards: SLC38A5; OMA:SLC38A5 - orthologs |
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Gene location (Human) |
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| Chr. | X chromosome (human)[1] |
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| Band | Xp11.23 | Start | 48,458,537 bp[1] |
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End | 48,470,260 bp[1] |
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Gene location (Mouse) |
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| Chr. | X chromosome (mouse)[2] |
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| Band | X|X A1.1 | Start | 8,137,372 bp[2] |
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End | 8,146,418 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - body of pancreas
- bone marrow cells
- stromal cell of endometrium
- upper lobe of left lung
- C1 segment
- mucosa of transverse colon
- left lobe of thyroid gland
- ganglionic eminence
- right lobe of thyroid gland
- right frontal lobe
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| Top expressed in | - fetal liver hematopoietic progenitor cell
- cumulus cell
- tibiofemoral joint
- lumbar subsegment of spinal cord
- left lung lobe
- blood
- pyloric antrum
- Ileal epithelium
- perirhinal cortex
- medial ganglionic eminence
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - glycine transmembrane transporter activity
- amino acid transmembrane transporter activity
| Cellular component | - integral component of membrane
- plasma membrane
- integral component of plasma membrane
- membrane
| Biological process | - amino acid transport
- glycine transport
- amino acid transmembrane transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr X: 48.46 – 48.47 Mb | Chr X: 8.14 – 8.15 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Solute carrier family 38 member 5 is a protein that in humans is encoded by the SLC38A5 gene. [5]
Function
The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine, asparagine, histidine, serine, alanine, and glycine across the cell membrane, but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000017483 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031170 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Solute carrier family 38 member 5". Retrieved 2017-10-07.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.