SCN4B |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4MZ2, 4MZ3 |
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Identifiers |
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Aliases | SCN4B, ATFB17, LQT10, Navbeta4, sodium voltage-gated channel beta subunit 4 |
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External IDs | OMIM: 608256; MGI: 2687406; HomoloGene: 18384; GeneCards: SCN4B; OMA:SCN4B - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 11 (human)[1] |
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| Band | 11q23.3 | Start | 118,133,377 bp[1] |
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End | 118,152,888 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 A5.2 | Start | 45,049,693 bp[2] |
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End | 45,065,450 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - external globus pallidus
- spinal ganglia
- putamen
- right hemisphere of cerebellum
- pons
- caudate nucleus
- lateral nuclear group of thalamus
- primary visual cortex
- Brodmann area 23
- trigeminal ganglion
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| Top expressed in | - triceps brachii muscle
- ankle
- vastus lateralis muscle
- sternocleidomastoid muscle
- temporal muscle
- knee joint
- digastric muscle
- extraocular muscle
- medial head of gastrocnemius muscle
- muscle of thigh
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - sodium channel regulator activity
- transmembrane transporter binding
- sodium channel activity
- voltage-gated ion channel activity
- voltage-gated sodium channel activity involved in cardiac muscle cell action potential
- voltage-gated sodium channel activity
| Cellular component | - voltage-gated sodium channel complex
- integral component of membrane
- membrane
- intercalated disc
- intrinsic component of plasma membrane
- plasma membrane
| Biological process | - cardiac muscle contraction
- sodium ion transmembrane transport
- sodium ion transport
- regulation of ion transmembrane transport
- cardiac muscle cell action potential involved in contraction
- ion transport
- regulation of sodium ion transmembrane transporter activity
- positive regulation of sodium ion transport
- AV node cell action potential
- regulation of heart rate by cardiac conduction
- membrane depolarization during cardiac muscle cell action potential
- regulation of ventricular cardiac muscle cell membrane repolarization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001142348 NM_001142349 NM_174934 |
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RefSeq (protein) | |
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NP_001135820 NP_001135821 NP_777594 |
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Location (UCSC) | Chr 11: 118.13 – 118.15 Mb | Chr 9: 45.05 – 45.07 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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