Prostaglandin-A1 Delta-isomerase
Prostaglandin-A1 Δ-isomerase | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||
EC no. | 5.3.3.9 | ||||||||
CAS no. | 9055-01-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
|
In enzymology, a Prostaglandin-A1 Δ-isomerase (EC 5.3.3.9) is an enzyme that catalyzes the chemical reaction
- (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate
Hence, this enzyme has one substrate, (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate (Prostaglandin A1 or PGA1), and one product, (13E)-(15S)-15-hydroxy-9-oxoprosta-11,13-dienoate (Prostaglandin C1).
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is (13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate Delta10-Delta11-isomerase. This enzyme is also called prostaglandin A isomerase.
References
- Polet H, Levine L (1975). "Metabolism of prostaglandins E, A, and C in serum". J. Biol. Chem. 250 (2): 351–7. PMID 234423.
- v
- t
- e
Isomerases: intramolecular oxidoreductases (EC 5.3)
- Triosephosphate isomerase
- Ribose-5-phosphate isomerase
- Mannose phosphate isomerase
- Glucose isomerase
- Phenylpyruvate tautomerase
- Oxaloacetate tautomerase
- 4-Oxalocrotonate tautomerase
- Steroid D-isomerase
- Isopentenyl-diphosphate delta isomerase
- Vinylacetyl-CoA D-isomerase
- Muconolactone D-isomerase
- Cholestenol Delta-isomerase (EBP)
- Methylitaconate D-isomerase
- Aconitate Delta-isomerase
- Enoyl CoA isomerase
- Prostaglandin-A1 Delta-isomerase
- 5-carboxymethyl-2-hydroxymuconate D-isomerase
- Isopiperitenone D-isomerase
- L-dopachrome isomerase
- Polyenoic fatty acid isomerase
This isomerase article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e