James Bethune

James Bethune may refer to:

  • James Beaton (or Bethune) (1473–1539), Scottish Roman Catholic bishop and Keeper of the Great Seal of Scotland
  • James Bethune (politician) (1840–1884), Canadian politician
  • James Gray Bethune (1793–1841), Canadian businessman and judge
  • James Lindesay-Bethune, 16th Earl of Lindsay (born 1955), Scottish businessman and politician
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