Isopropamide
Chemical compound
- A03AB09 (WHO)
- US: ℞-only and Unscheduled
- In general: unscheduled
- 4-amino-N,N-diisopropyl-N-methyl-4-oxo-3,3-diphenylbutan-1-aminium
- 7492-32-2 N
- 3775
- DB01625 Y
- 3643 Y
- 8B9I31H724
- ChEMBL1201232 N
- DTXSID9023174
- Interactive image
- O=C(N)C(c1ccccc1)(c2ccccc2)CC[N+](C(C)C)(C(C)C)C
InChI
- InChI=1S/C23H32N2O/c1-18(2)25(5,19(3)4)17-16-23(22(24)26,20-12-8-6-9-13-20)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3,(H-,24,26)/p+1 Y
- Key:JTPUMZTWMWIVPA-UHFFFAOYSA-O Y
Isopropamide (R79) is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders involving hyperacidity (gastrointestinal acidosis) and hypermotility. Chemically, it contains a quaternary ammonium group. It is most often provided as an iodide salt, but is also available as a bromide or chloride salt. It was discovered at Janssen Pharmaceutica in 1954.
References
Further reading
- Seeherman R (October 1957). "Isopropamide iodide: a long-acting anticholinergic". Delaware Medical Journal. 29 (10): 265–9. PMID 13473394.
- Boss Jr EG, Buchanan GC (November 1957). "Effect of isopropamide iodide on basal gastric secretion in the human". Gastroenterology. 33 (5): 730–6. doi:10.1016/S0016-5085(19)35625-2. PMID 13480414.
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Drugs for functional gastrointestinal disorders (A03)
functional
bowel
disorders
Antimuscarinics |
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Phosphodiesterase inhibitors | |||||
Acting on serotonin receptors |
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Other |
and derivatives
(antimuscarinics)
- Tertiary amines: Atropine
- Hyoscyamine
- Quaternary ammonium compounds:
- Cimetropium bromide
- Fentonium bromide
- Methylatropine
- Primarily dopamine antagonists
- 5-HT4 agonists
- Acotiamide
- Ilebopride
- Mosapride
This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |
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