Haloprogin
- D01AE11 (WHO)
- US: Not available
- 1,2,4-Trichloro-5-[(3-iodoprop-2-yn-1-yl)oxy]benzene
- 777-11-7 Y
- 3561
- DB00793 Y
- 3440 Y
- AIU7053OWL
- D00339 Y
- ChEMBL1289 Y
- DTXSID9046865
- Interactive image
- Clc1cc(OCC#CI)c(Cl)cc1Cl
- InChI=1S/C9H4Cl3IO/c10-6-4-8(12)9(5-7(6)11)14-3-1-2-13/h4-5H,3H2 Y
- Key:CTETYYAZBPJBHE-UHFFFAOYSA-N Y
Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections.[1] It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.
Action
Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over-the-counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.[2]
Haloprogin had a high incidence of side effects including: irritation, burning, vesiculation (blisters), scaling, and itching. It has since been discontinued due to the emergence of more modern antifungals with fewer side effects.[3]
References
- ^ Rudolph RI (December 1979). "Haloprogin as treatment for fungal infections". Clinical and Experimental Dermatology. 4 (4): 548. doi:10.1111/j.1365-2230.1979.tb01656.x. PMID 161212. S2CID 71471801.
- ^ "Haloprogin". Drugs@FDA. Food and Drug Administration. Retrieved 2007-02-17.
- ^ "Haloprogin". DrugBank. University of Alberta. Nov 6, 2006. Retrieved 2007-02-17.
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- bromochlorosalicylanilide
- chlorophetanol
- chlorphenesin
- ciclopirox
- crystal violet
- dimazole
- ethylparaben
- haloprogin‡
- polynoxylin
- potassium iodide#
- salicylic acid
- selenium disulfide#
- sodium thiosulfate#
- sulbentine
- taurolidine
- ticlatone
- tolciclate
- tolnaftate
- tribromometacresol
- undecylenic acid
- Whitfield's ointment#
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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