HOCPCA
Chemical compound
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Preferred IUPAC name 3-Hydroxycyclopent-1-ene-1-carboxylic acid | |
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Chemical formula | C6H8O3 |
Molar mass | 128.127 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
HOCPCA (3-hydroxycyclopent-1-enecarboxylic acid) is a compound with an affinity for the GHB receptor 39 times greater than that of GHB itself.[1]
See also
- T-HCA
References
- ^ Wellendorph P, Høg S, Greenwood JR, de Lichtenberg A, Nielsen B, Frølund B, Brehm L, Clausen RP, Bräuner-Osborne H (2005). "Novel Cyclic γ-Hydroxybutyrate (GHB) Analogs with High Affinity and Stereoselectivity of Binding to GHB Sites in Rat Brain". The Journal of Pharmacology and Experimental Therapeutics. 315 (1): 346–351. doi:10.1124/jpet.105.090472. PMID 16014570.
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GHB receptor modulators
(ligands)
GHBRTooltip GHB receptor |
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GABABTooltip γ-Aminobutyric acid B receptor |
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(blockers)
MCTsTooltip Monocarboxylate transporters | |
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SMCTsTooltip Sodium-coupled monocarboxylate transporters | |
VIATTTooltip Vesicular inhibitory amino acid transporter |
(inhibitors)
SSRTooltip Succinic semialdehyde reductase | |
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GHBDHTooltip 4-Hydroxybutyrate dehydrogenase |
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HOTTooltip Hydroxyacid-oxoacid transhydrogenase | |
ADHTooltip Alcohol dehydrogenase | |
ALDHTooltip Aldehyde dehydrogenase |
- See also
- Receptor/signaling modulators
- GABA receptor modulators
- Glutamate receptor modulators
- Glycine receptor modulators
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