Fluperolone acetate
Chemical compound
- D07AB05 (WHO)
- (2S)-1-[(1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-14-yl]-1-oxopropan-2-yl acetate
- 2119-75-7 Y
- 66257
- 59639
- DOL7Q9DPF9
- D04225
- DTXSID50895064
- Interactive image
- C[C@@H](C(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O)OC(=O)C
InChI
- InChI=1S/C24H31FO6/c1-13(31-14(2)26)20(29)23(30)10-8-17-18-6-5-15-11-16(27)7-9-21(15,3)24(18,25)19(28)12-22(17,23)4/h7,9,11,13,17-19,28,30H,5-6,8,10,12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
- Key:HHPZZKDXAFJLOH-QZIXMDIESA-N
Fluperolone acetate is a corticosteroid. It has been used topically.[1]
References
- ^ Thorne N (March 1963). "A clinical trial of Fluperolone, a new topical steroid". Postgraduate Medical Journal. 39 (449): 159–60. doi:10.1136/pgmj.39.449.159. PMC 2482046. PMID 13984971.
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Glucocorticoids and antiglucocorticoids (D07, H02)
Natural | |
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Synthetic |
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- Antagonists: Aglepristone
- Ketoconazole
- Mifepristone
- Ulipristal acetate
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Glucocorticoid receptor modulators
- Mineralocorticoids and antimineralocorticoids
- List of corticosteroids
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