Fenethazine
Chemical compound
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Other names | Phenethazinum, Phenethazine, Phenetazine; RP-3015, SC-1627, WY-1143 |
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ECHA InfoCard | 100.007.570 |
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Formula | C16H18N2S |
Molar mass | 270.39 g·mol−1 |
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Fenethazine (INN) (brand names Anergen, Contralergial, Ethysine, Etisine, Lisergan, Lysergan; former developmental code names RP-3015, SC-1627, WY-1143), or phenethazine, is a first-generation antihistamine of the phenothiazine group.[1] Promethazine and chlorpromazine, were derived from fenethazine.[2] Fenethazine, in turn, was derived from phenbenzamine.[3]
References
- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 434–. ISBN 978-1-4757-2085-3.
- ^ Dörwald FZ (4 February 2013). Lead Optimization for Medicinal Chemists: Pharmacokinetic Properties of Functional Groups and Organic Compounds. John Wiley & Sons. pp. 301–. ISBN 978-3-527-64565-7.
- ^ Sneader W (23 June 2005). Drug Discovery: A History. John Wiley & Sons. pp. 404–. ISBN 978-0-471-89979-2.
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Antihistamines (R06)
- Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine)
- Carbinoxamine
- Chlorphenoxamine
- Clemastine
- Diphenhydramine (+naproxen)
- Diphenylpyraline
- Doxylamine
- Ebastine
- Orphenadrine
- Diphenylmethylpiperazines: Buclizine
- Cetirizine
- Chlorcyclizine
- Cinnarizine
- Cyclizine
- Etodroxizine
- Hydroxyzine
- Meclizine
- Oxatomide
- Phenylpyridinylpropanamines: Brompheniramine
- Chlorphenamine
- Dexbrompheniramine (+pseudoephedrine)
- Dexchlorpheniramine (+betamethasone)
- Pheniramine
- Phenylpiperazines: Antidepressants (e.g., trazodone)
- Phenbenzamine
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