FAM73B

Protein-coding gene in the species Homo sapiens
MIGA2
Identifiers
AliasesMIGA2, C9orf54, FAM73B, family with sequence similarity 73 member B, mitoguardin 2
External IDsOMIM: 616774; MGI: 1922035; HomoloGene: 13125; GeneCards: MIGA2; OMA:MIGA2 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for MIGA2
Genomic location for MIGA2
Band9q34.11Start129,036,621 bp[1]
End129,072,082 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for MIGA2
Genomic location for MIGA2
Band2|2 BStart30,364,233 bp[2]
End30,385,521 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pancreatic ductal cell

  • apex of heart

  • right hemisphere of cerebellum

  • mucosa of transverse colon

  • granulocyte

  • skin of arm

  • right lobe of thyroid gland

  • body of stomach

  • cerebellar vermis

  • left ventricle
Top expressed in
  • brown adipose tissue

  • substantia nigra

  • motor neuron

  • right ventricle

  • left lobe of liver

  • medial vestibular nucleus

  • medial geniculate nucleus

  • deep cerebellar nuclei

  • medial dorsal nucleus

  • tunica adventitia of aorta
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
  • protein homodimerization activity
  • protein heterodimerization activity
Cellular component
  • integral component of membrane
  • mitochondrial outer membrane
  • membrane
  • mitochondrion
  • integral component of plasma membrane
Biological process
  • mitochondrial fusion
  • bone development
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84895

108958

Ensembl

ENSG00000148343

ENSMUSG00000026858

UniProt

Q7L4E1

Q8BK03

RefSeq (mRNA)

NM_032809
NM_001329990

NM_001242407
NM_175392

RefSeq (protein)

NP_001316919
NP_116198

NP_001229336
NP_780601
NP_001365835
NP_001365836
NP_001365838

NP_001365840
NP_001394213

Location (UCSC)Chr 9: 129.04 – 129.07 MbChr 2: 30.36 – 30.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The family with sequence similarity 73, member B, also known as FAM73B, is a human gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000148343 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026858 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: family with sequence similarity 73, member B". Retrieved 2011-08-30.

Further reading

  • Otsuki T, Ota T, Nishikawa T, et al. (2005). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.