Eprinomectin
Veterinary anti-parasitic medication
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Trade names | Eprinex |
Other names | MK-397, 4"-epi-acetylamino-4"-deoxy-avermectin B1a (4"R)-4"-(acetylamino)-5-O-demethyl-4"-deoxyavermectin A1a |
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Routes of administration | Topical |
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Bioavailability | 29%[2] |
Protein binding | >99%[2] |
Onset of action | 24 hours[2] |
Elimination half-life | 8–36 days[2] |
Duration of action | 7–10 days[2] |
Excretion | Feces (17–19.8%), urine (0.35%), milk (0.32–0.54%)[2] |
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Formula | C50H75NO14 |
Molar mass | 914.143 g·mol−1 |
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Other names | 4"-epi-acetylamino-4"-deoxy-avermectin B1b |
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Formula | C49H73NO14 |
Molar mass | 900.116 g·mol−1 |
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Eprinomectin is an avermectin used as a veterinary topical endectocide.[1][3] It is a mixture of two chemical compounds, eprinomectin B1a and B1b.[4]
References
- ^ a b "Eprinex Pour-On For Beef And Dairy Cattle- eprinomectin solution". DailyMed. 28 February 2022. Retrieved 16 March 2023.
- ^ a b c d e f "Committee for Veterinary Medicinal Products: Eprinomectin" (PDF). The European Agency for the Evaluation of Medicinal Products. June 1996. Retrieved 2020-05-24.
- ^ Shoop WL, Egerton JR, Eary CH, Haines HW, Michael BF, Mrozik H, et al. (November 1996). "Eprinomectin: a novel avermectin for use as a topical endectocide for cattle". International Journal for Parasitology. 26 (11): 1237–42. doi:10.1016/s0020-7519(96)00123-3. PMID 9024867.
- ^ "UNII - 75KP30FD8O". U.S. Food and Drug Administration. Retrieved 16 March 2023.
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