Clefamide
Chemical compound
- P01AC02 (WHO)
- 2,2-Dichloro-N-(2-hydroxyethyl)-N-[[4-(4-nitrophenoxy)phenyl]methyl]
- 3576-64-5
- 71819
- 64843 Y
- 4AZ2V8K4EK
- D07354 Y
- ChEMBL1788400
- DTXSID30189296
- Interactive image
- ClC(Cl)C(=O)N(CCO)Cc2ccc(Oc1ccc(cc1)[N+]([O-])=O)cc2
InChI
- InChI=1S/C17H16Cl2N2O5/c18-16(19)17(23)20(9-10-22)11-12-1-5-14(6-2-12)26-15-7-3-13(4-8-15)21(24)25/h1-8,16,22H,9-11H2 Y
- Key:ODCUSWJXZDHLKV-UHFFFAOYSA-N Y
Clefamide (trade name Mebinol) is an antiprotozoal agent that was used to treat amoebiasis in the 1960s.[1] There is no evidence for any later use of the drug.
References
- ^ Rodrigues LD, Jafferian PA, Vilella M, Costa AA, de Mello EB (November 1968). "[Comparative study on 3 amebicides: teclozine, clefamide and a combination of clefamide and iodo-chloro-oxyquinolines and streptomycin]". Hospital. 74 (5): 1563–73. PMID 5305335.
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Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)
Tissue amebicides |
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Luminal amebicides |
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Other/ungrouped |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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