Cafaminol
Chemical compound
- None
- In general: ℞ (Prescription only)
- 8-[(2-hydroxyethyl)(methyl)amino]-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
- 30924-31-3
- 35685
- 32824
- 0L1S25NC1L
- ChEMBL2104570
- DTXSID60184916
- Interactive image
- O=C2N(c1nc(n(c1C(=O)N2C)C)N(CCO)C)C
InChI
- InChI=1S/C11H17N5O3/c1-13(5-6-17)10-12-8-7(14(10)2)9(18)16(4)11(19)15(8)3/h17H,5-6H2,1-4H3
- Key:ZGNRRVAPHPANFI-UHFFFAOYSA-N
Cafaminol (brand names Rhinetten, Rhinoptil), also known as methylcoffanolamine, is a vasoconstrictor and anticatarrhal of the methylxanthine family related to caffeine which is used as a nasal decongestant in Germany.[1][2][3][4][5][6] It was introduced in 1974 and was still in use as of 2000.[3][2]
References
- ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 205–. ISBN 978-1-4757-2085-3.
- ^ a b Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 157–. ISBN 978-3-88763-075-1.
- ^ a b William Andrew Publishing (22 October 2013). Pharmaceutical Manufacturing Encyclopedia. Elsevier. pp. 784–. ISBN 978-0-8155-1856-3.
- ^ Szirmai E (1969). "[A new treatment for colds using a new caffeine derivative, methylcoffanolamine]". Praxis (in German). 58 (13): 412–4. PMID 5818666.
- ^ Walther H, Köhler E (1979). "[Human pharmacologic studies on the biologic availability and resorption of cafaminol (AWD) (proceedings)]". Pharmazie (in German). 34 (5–6): 375–6. PMID 515164.
- ^ Rogowski M, Chodynicki S (1985). "[Use of the preparation Cafaminol in the treatment of acute rhinitis]". Wiad. Lek. (in Polish). 38 (20): 1437–40. PMID 3913153.
- v
- t
- e
Decongestants and other nasal preparations (R01)
Sympathomimetics, plain | |
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Antiallergic agents, excluding corticosteroids | |
Corticosteroids | |
Other nasal preparations |
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Combination products |
Sympathomimetics
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III