CACNB3 |
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Identifiers |
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Aliases | CACNB3, CAB3, CACNLB3, calcium voltage-gated channel auxiliary subunit beta 3 |
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External IDs | OMIM: 601958; MGI: 103307; HomoloGene: 20187; GeneCards: CACNB3; OMA:CACNB3 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 12 (human)[1] |
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| Band | 12q13.12 | Start | 48,813,794 bp[1] |
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End | 48,828,941 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 15 (mouse)[2] |
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| Band | 15 F1|15 54.64 cM | Start | 98,528,721 bp[2] |
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End | 98,542,410 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ganglionic eminence
- frontal pole
- right uterine tube
- right frontal lobe
- right ovary
- left ovary
- right hemisphere of cerebellum
- endothelial cell
- prefrontal cortex
- stromal cell of endometrium
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| Top expressed in | - habenula
- superior frontal gyrus
- primary visual cortex
- entorhinal cortex
- dentate gyrus of hippocampal formation granule cell
- perirhinal cortex
- CA3 field
- olfactory epithelium
- lumbar spinal ganglion
- external carotid artery
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - protein kinase binding
- voltage-gated ion channel activity
- voltage-gated calcium channel activity
- high voltage-gated calcium channel activity
- calcium channel activity
- protein binding
- calcium channel regulator activity
| Cellular component | - apical plasma membrane
- membrane
- cytosol
- plasma membrane
- voltage-gated calcium channel complex
- L-type voltage-gated calcium channel complex
- cytoplasm
| Biological process | - membrane depolarization
- regulation of ion transmembrane transport
- ion transport
- regulation of voltage-gated calcium channel activity
- neuromuscular junction development
- calcium ion transmembrane transport
- calcium ion transport
- regulation of membrane repolarization during action potential
- calcium ion transport into cytosol
- protein localization to plasma membrane
- chemical synaptic transmission
- calcium ion transmembrane transport via high voltage-gated calcium channel
- detection of mechanical stimulus involved in sensory perception of pain
- positive regulation of protein targeting to membrane
- cellular response to oxygen-glucose deprivation
- negative regulation of voltage-gated calcium channel activity
- positive regulation of voltage-gated calcium channel activity
- positive regulation of high voltage-gated calcium channel activity
- regulation of membrane hyperpolarization
- negative regulation of detection of mechanical stimulus involved in sensory perception of touch
- positive regulation of excitatory postsynaptic potential
- T cell receptor signaling pathway
- cardiac conduction
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_000725 NM_001206915 NM_001206916 NM_001206917 |
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NM_001044741 NM_001286226 NM_007581 NM_001356543 |
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RefSeq (protein) | |
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NP_000716 NP_001193844 NP_001193845 NP_001193846 |
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NP_001038206 NP_001273155 NP_031607 NP_001343472 |
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Location (UCSC) | Chr 12: 48.81 – 48.83 Mb | Chr 15: 98.53 – 98.54 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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