Bamifylline
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Preferred IUPAC name 8-Benzyl-7-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione | |
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3D model (JSmol) |
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ECHA InfoCard | 100.116.522 |
PubChem CID |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C20H27N5O3 |
Molar mass | 385.46008 |
Pharmacology | |
R03DA08 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.[1][2]
See also
References
- ^ Tomai, F; Crea, F; Gaspardone, A; Versaci, F; De Paulis, R; Polisca, P; Chiariello, L; Gioffrè, PA (June 1996). "Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty". European Heart Journal. 17 (6): 846–53. doi:10.1093/oxfordjournals.eurheartj.a014965. PMID 8781823.
- ^ Kofman, J; Grosclaude, M; Ouechni, MM; Perrin-Fayolle, M (1982). "Comparative effects of bamifylline and theophylline on allergenic bronchospasm induced by the provocative inhalation test: double-blind cross-over study". Le Poumon et le Cœur (in French). 38 (3): 197–202. PMID 6752929.
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Short-acting β2 agonists | |
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Long-acting β2 agonists |
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Ultra-long-acting β2 agonists | |
Other |
muscarinic antagonist
Leukotriene antagonists | |
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Arachidonate 5-lipoxygenase inhibitors | |
Thromboxane receptor antagonists | |
Non-xanthine PDE4 inhibitors |
- Aclidinium bromide/formoterol
- Beclometasone/formoterol
- Beclometasone/formoterol/glycopyrronium bromide
- Budesonide/formoterol
- Budesonide/glycopyrronium bromide/formoterol
- Fluticasone furoate/umeclidinium bromide/vilanterol
- Fluticasone furoate/vilanterol
- Fluticasone propionate/salmeterol
- Glycopyrronium bromide/formoterol
- Indacaterol/glycopyrronium bromide
- Indacaterol/glycopyrronium bromide/mometasone
- Indacaterol/mometasone
- Ipratropium bromide/salbutamol
- Mometasone/formoterol
- Salbutamol (albuterol)/budesonide
- Theophylline/ephedrine
- Theophylline/ephedrine/hydroxyzine
- Theophylline/ephedrine/phenobarbital
- Umeclidinium bromide/vilanterol
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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