ASZ1

Protein-coding gene in the species Homo sapiens
ASZ1
Identifiers
AliasesASZ1, ALP1, ANKL1, C7orf7, CT1.19, GASZ, Orf3, ankyrin repeat, SAM and basic leucine zipper domain containing 1
External IDsOMIM: 605797; MGI: 1921318; HomoloGene: 11374; GeneCards: ASZ1; OMA:ASZ1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for ASZ1
Genomic location for ASZ1
Band7q31.2Start117,363,222 bp[1]
End117,428,123 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for ASZ1
Genomic location for ASZ1
Band6|6 A2Start18,050,963 bp[2]
End18,109,060 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • gonad

  • right testis

  • left testis

  • buccal mucosa cell

  • corpus callosum

  • sperm

  • stromal cell of endometrium

  • lower lobe of lung

  • granulocyte
Top expressed in
  • spermatocyte

  • primary oocyte

  • zygote

  • secondary oocyte

  • spermatid

  • seminiferous tubule

  • Gonadal ridge

  • left lung lobe

  • morula

  • urethra
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • signal transducer activity
Cellular component
  • cytoplasm
  • pi-body
Biological process
  • male meiotic nuclear division
  • multicellular organism development
  • cell differentiation
  • meiosis
  • spermatogenesis
  • DNA methylation involved in gamete generation
  • gene silencing
  • signal transduction
  • piRNA metabolic process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

136991

74068

Ensembl

ENSG00000154438

ENSMUSG00000010796

UniProt

Q8WWH4
Q49AP3

Q8VD46

RefSeq (mRNA)

NM_001301821
NM_001301822
NM_130768

NM_023729

RefSeq (protein)

NP_001288750
NP_001288751
NP_570124

NP_076218

Location (UCSC)Chr 7: 117.36 – 117.43 MbChr 6: 18.05 – 18.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 is a protein that in humans is encoded by the ASZ1 gene.[5][6][7]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000154438 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000010796 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Yan W, Rajkovic A, Viveiros MM, Burns KH, Eppig JJ, Matzuk MM (May 2002). "Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper". Mol Endocrinol. 16 (6): 1168–84. doi:10.1210/mend.16.6.0864. PMID 12040005.
  6. ^ Zenklusen JC, Conti CJ, Green ED (Mar 2001). "Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31". Nat Genet. 27 (4): 392–8. doi:10.1038/86891. PMID 11279520. S2CID 2749283.
  7. ^ "Entrez Gene: ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1".

External links

Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Zink D, Amaral MD, Englmann A, et al. (2004). "Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei". J. Cell Biol. 166 (6): 815–25. doi:10.1083/jcb.200404107. PMC 2172106. PMID 15364959.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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