2,4-Dichlorobenzyl alcohol
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Preferred IUPAC name (2,4-Dichlorophenyl)methanol | |
Other names Dybenal Rapidosept Myacide SP | |
Identifiers | |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.015.646 |
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InChI
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Properties | |
Chemical formula | C7H6Cl2O |
Molar mass | 177.02 g·mol−1 |
Melting point | 57 to 60 °C (135 to 140 °F; 330 to 333 K) |
Boiling point | 150 °C (302 °F; 423 K) 25 mmHg |
Pharmacology | |
R02AA03 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Cofsils, Strepsils, Lorsept, and Gorpils. It is also an ingredient in the European product Neo Borocillina.[1] A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (0.6 mg) has been found to deactivate respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus.[2] A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5 to 10 minutes after brushing.[3]
References
- ^ "Neo Borocillina". drugs.com. Archived from the original on 2020-09-13. Retrieved 2018-01-23.
- ^ Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral Chemistry & Chemotherapy. 16 (2): 129–34. doi:10.1177/095632020501600205. PMID 15889535.
- ^ Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study". Acta Odontol Scand. 52 (6): 335–45. doi:10.3109/00016359409029031. PMID 7887143.
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Alcohols
Alcohols found in alcoholic drinks |
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Medical alcohol |
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Toxic alcohols |
alcohols (1°)
Methanol | |
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Ethanol |
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Butanol |
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Straight-chain saturated C1 — C9 |
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Straight-chain saturated C10 — C19 |
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Straight-chain saturated C20 — C29 |
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Straight-chain saturated C30 — C39 |
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Straight-chain saturated C40 — C49 |
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alcohols (2°)
alcohols (3°)
- 2-Methyl-2-pentanol
- 2-Methylheptan-2-ol
- 2-Methylhexan-2-ol
- 3-Methyl-3-pentanol
- 3-Methyloctan-3-ol
- Diacetone alcohol
- Ethchlorvynol
- Methylpentynol
- Nonafluoro-tert-butyl alcohol
- tert-Amyl alcohol
- tert-Butyl alcohol
- Triphenylethanol
- Triphenylmethanol
Monohydric alcohols |
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Dihydric alcohols | |
Trihydric alcohols | |
Polyhydric alcohols (sugar alcohols) |
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- Benzyl alcohol
- 2,4-Dichlorobenzyl alcohol
- 3-Nitrobenzyl alcohol
fatty alcohols
unsaturated
fatty alcohols
- 3-Methyl-3-pentanol
- Erucyl alcohol
- Linolenyl alcohol
- Linoleyl alcohol
- Oleyl alcohol
- Palmitoleyl alcohol
- tert-Amyl alcohol
- tert-Butyl alcohol
C1 — C7 |
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Deoxy sugar alcohols | |
Cyclic sugar alcohols | |
Glycylglycitols |
Monoterpene alcohols | |
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Sesquiterpene alcohols | |
Diterpene alcohols |
- 1,3-Difluoro-2-propanol
- 2,2,2-Trifluoroethanol
- 2-Fluoroethanol
- Nonafluoro-tert-butyl alcohol
- Trifluoromethanol
- Category